Intellectual Property
Intellectual Property Portfolio
Three decades of invention. A validated portfolio of patents, trademarks, and proprietary methodologies spanning multiple sterilization and purification domains.
1996 — 2026
Thirty years of validated invention.
Patent Portfolio
PuroGen's patent portfolio covers core system architectures, process methodologies, and chemical formulations across multiple sterilization and purification domains.
SteriFlex™
Patented VHP Sterilization Platform
Originally filed as part of PuroGen's programmable sterilization architecture
Claims Summary
Programmable vaporized hydrogen peroxide (VH₂O₂) sterilization system with adjustable dwell times, reagent dosing, vacuum parameters, and high-humidity capability. Claims cover the parametric control architecture, cycle optimization methodology, and integration with validation instrumentation.
Applications
TheBOX®
Patented Enclosed VHP Chamber
Patent granted for enclosed sterilization and infusion chamber design
Claims Summary
Enclosed sterilization chamber designed for VHP and Reactive Oxygen processing. Claims cover chamber architecture, gas distribution methodology, environmental control systems, and integration pathways for cleanroom, laboratory, and manufacturing environments.
Applications
T10⁶®
Two-Stage Non-Irradiated Tissue Sterilization Process
Developed 2006 — nearly two decades before industry adoption of non-irradiated methods
Claims Summary
Non-irradiated terminal sterilization of allograft tissue — a two-stage process comprising a proprietary cold sterilization stage and VHP terminal sterilization. Claims cover process parameters, methodology for achieving terminal sterilization while preserving osteoinductivity and growth factors, and the original scCO₂ embodiment developed in 2006.
Applications
Reactive Oxygen™
Advanced Oxidation Chemistry
Proprietary formulation with ongoing development
Claims Summary
Proprietary reactive oxygen species formulation for surface decontamination and environmental bioburden reduction. Process methodology encompasses generation, delivery, and controlled decomposition of reactive oxygen species for regulated applications.
Applications
Registered Trademarks
PuroGen's trademark portfolio reflects the breadth of its commercial platform.
SteriFlex™
Trademark
TheBOX®
Registered
T10⁶®
Registered
Reactive Oxygen™
Trademark
PuroGen®
Registered
BoxPurify®
Registered
BoxInfuse®
Registered
Beyond Patents
Proprietary knowledge that cannot be replicated.
PuroGen's intellectual property extends beyond patents to include proprietary process parameters, validation methodologies, and formulation know-how developed over decades of regulated sterilization and purification work.
This institutional knowledge — the accumulated understanding of how materials behave under specific conditions, how regulatory requirements translate into process design, and how validation methodologies evolve across domains — represents an asset that cannot be replicated through reverse engineering or independent development.
IP Underpinning
The three operational departures that define PuroGen's platform — driven substrate penetration, a moisture operating range up to ~20% RH, and product-specific programmable cycle architecture — are not marketing claims. They are the subject matter of PuroGen's patent portfolio. The claims represent sustained original work at the bench, not technology acquired or adapted from third-party IP.
Three departures from conventional VHPInterested in PuroGen's technology portfolio?
This portfolio is available to corporate development teams, technology licensing professionals, and strategic partners for confidential discussion.